Ciencia Internacional

Wolbachia Genes For Combating Zika

Nature Magazine
Nature Magazine

Wolbachia bacteria infect insects and can cause mating incompatibilities, an outcome that is used to fight insect-transmitted disease. The proposed genes responsible illuminate this process and the disease-control mechanisms.


  • Wolbachia bacteria can infect the male and female germ line of insects.
  • This bacterial infection can manipulate insect reproductive outcomes to benefit Wolbachia transmission through a phenomenon known as cytoplasmic incompatibility.
  • Wolbachia has promise as a potent means of pest control and is being used to limit mosquito-transmitted human diseases such as dengue and Zika.
  • Understanding the molecular basis of cytoplasmic incompatibility could aid efforts to improve disease-control strategies.

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